millions treated for hypothyroidism at risk for lung cancer millions treated for hypothyroidism at risk for lung cancer

Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer This is a horrible disease that ravages the body. Join the forum, it's quick and easy . Hashimoto's disease - Symptoms and causes - Mayo Clinic There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a TSH suppressor. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic self-fulfilling prophecy if you will. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Unfortunately, it's quite typical. J Endocrinol Invest. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. by D.ap Tue Feb 21, 2017 10:40 am, Powered by phpBB Forum Software phpBB Limited. [10] Hofer T, Desbaillets I, Hpfl G, Wenger RH, Gassmann M: Characterization of HIFD-1 alpha overexpressing Hela cells and implication for gene therapy. The authors of the study pointed out that levothyroxine (T4) treatment can lead to medication-induced (iatrogenic) thyroid over-activity (hyperthyroidism) and oxidative stress that can lead to a significant patient discomfort. [learn more: Is Drug-Based Medicine a Form of Human Sacrifice?] Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study. Sub-laboratory hypothyroidism and the empirical use of Armour thyroid.Altern Med Rev. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Correlation is when two things seem to happen at the same time, in the same place, and/or in the same population. [4], DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. The aim of the study was to assess the occurrence and nature of immune-related endocrine adverse events (irAEs) among patients with non-small-cell lung cancer (NSCLC) treated with nivolumab. Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the "low thyroid," why call chemical poisoning "hypothyroidism"? [13] Hollowell JG, Staehling NW, Flanders WD, et al. This is a news report of the research, so I can't learn the details of how the science was conducted. PLoSone 2011, 11:e27547. Lung cancer survivors support group and discussion community, http://www.greenmedinfo.com/blog/study-millions-treated-hypothyroidism-risk-lung-cancers?utm_source=www.GreenMedInfo.com&utm_campaign=2189ddd3c1-Greenmedinfo&utm_medium=email&utm_term=0_193c8492fb-2189ddd3c1-87046221. 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A place for patients and relatives. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. For more information, please see our It's usually based on the results of blood tests. I bet in the previous discussion, if there was one, we would have concluded it was likely that it was because people are generally not put on enough levothyroxine. millions treated for hypothyroidism at risk for lung cancer Kelly Mellott on LinkedIn: Nodify Lung: Nodule Risk Assessment | Biodesix The study looked at the prevalence of breast, colorectal, gastric and lung cancer in 18 Italian Regions during 2010 and correlated this data with sales of LT4 in 2009, focusing on women aged 30-84. The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. I very much appreciate the information you shared. Thyroid dysfunction after immune checkpoint inhibitor treatment in a [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. Reddit and its partners use cookies and similar technologies to provide you with a better experience. All the more reason to prescribe T3, I say! They compared sale of, "However, the impression we get from our experience, Health, Studies, Supps & Pharmaceuticals. ', Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. However, I do not believe it was out of the blue now. rocket fuel, pesticides, fluoride, which induce low thyroid function. As I have lung cancer and just recently was diagnosed hypothyroidI am very interested as to what you have to say about this connection.your personal insight and any books, websites would be appreciated.you may email me if you prefer. 1). So I will leave it as a simple thank you for passing this along. If I can help someone, fine. Increased sleepiness. elevated TSH, without actually improving the overall physiological situation, nor the patients subjective experience of well being. Intuition and Trust: a Personal Journey Through Ancient Pathways, Meditation, Yoga, Grounding & Mindfulness, Levothyroxine and lung cancer in females: the importance of oxidative stress, 2013 announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs, Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). undefined will no longer be visible to you including posts, replies, and photos. PMID: 11929079, [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. Other research indicating that increased thyroid activity (hyperthyroidism) contributes to lung cancer pathogenesis was presented, including: Recently T4 has been reported as one of the several endogenous factors capable of supporting proliferation of lung cancer cells. Results indicate that treatment with levothyroxine was linked with significantly increased mortality (hazard ratio = 1.19). "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Also, what is oxidised stress??? Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as "hypothyroidism"? If you are already a member, please, Levothyroxine and lung cancer in females: the importance of oxidative stress, recent announcement by a National Cancer Institute, T-score based definition of osteoporosis and osteopenia, 30-billion dollar a year market in statin drugs. Share your experience, learn from others. Why not simply call it selenium deficiency? Monaldi Arch Chest Dis 2003, 59:140145. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer Posted on: Monday, August 12th 2013 at 7:15 am Written By: Sayer Ji, Founder A new study has. She wrote about a product called Thyrtophin PMG. hyperthyroidism. Medical Authoritys System Kills: FDA-Approved Dru Cognitive Impairment, Memory Loss and Alzheimer's Soy Lecithin: How It Negatively Affects Your Healt Cannabis Oil Cures Cancer -Lincoln Horsley's Story New Information Dissolves Illusions About Vaccines Grounding Helps Thin Dangerously Thick Blood and F Tart Cherries Relieve Osteoarthritis Pain, Lieberman's Massive Connections To Big Pharma, Utopian 'Harvest Your Own' Groceries Coming Up. [3]Faber J, Poulsen S, Iversen P, Kirkegaard C: Thyroid hormone turnover in patients with small cell carcinoma of the lung. At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. I have so much to say about this I could write a book. Angiology 2000, 51:S65S68. weight loss, anorexia). " The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. I've been on synthroid for 20+ years, scary. As you know, I appreciate people posting links that help us learn more about lung cancer, too. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. New Cholesterol Drug Guaranteed to Prematurely Kil Beware the Walgreens travel vaccination scam. Tokushima J Exp Med 1991, 38:2535. If it's high, the test is done again, along with a blood test for the thyroid hormone T-4. Researchers are currently studying. A couple of caveats to note in this study: The authors found a statistical correlation between the increase in sales of the thyroid medicine Synthroid, and an increase in lung cancer in Italy. [8] van Doorn J, Roelfsema F, van der Heide D: Concentration of thyroxine and 3,5,3'-triiodotyronine in several rat tissue in vivo: the effect of hypothyroidism. I was sure that the paper had been discussed here shortly after publication in 2013, but cannot find the thread! millions treated for hypothyroidism at risk for lung cancer Objectives: To examine site-specific cancer incidence and mortality and to evaluate the radiation dose-response association after RAI treatment for hyperthyroidism. Endocrinology 2008, 149:22412250. Baked or Fried avocado fries [Vegetarian]. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. In an attempt to show causation, the article notes "patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. It is very tormenting (for me anyhow) to not know why I got this disease. It does not necessarily imply one thing caused the other. CRF encompasses physical, emotional, and/or cognitive tiredness; is related to cancer or cancer treatments; and interferes with multiple dimensions of health-related quality of life (1-3).CRF is poorly understood, underrecognized, and undertreated. I am going to go for a walk with my dog :)). However, they pointed out that the opposite was actually described, and that hypothyroidism reduces the aggressiveness of some cancers because of the presence of thyroid hormone receptors on cancer cells, and spontaneous hypothyroidism may delay onset or reduce aggressiveness of cancers.[1]. Due to excessive bot signups along with nefarious actors we are limiting forum registration. Thyroid dysfunction after immune checkpoint inhibitor treatment in a Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism. El almacenamiento o acceso tcnico es estrictamente necesario para el propsito legtimo de permitir el uso de un servicio especfico explcitamente solicitado por el abonado o usuario, o con el nico propsito de llevar a cabo la transmisin de una comunicacin a travs de una red de comunicaciones electrnicas. Angiology 2000, 51:S65S68. SayerJiis founder ofGreenmedinfo.com, a reviewer at theInternational Journal of Human Nutrition and Functional Medicine,Co-founder and CEO of Systome Biomed, Vice Chairman of the Board of theNational Health Federation, SteeringCommittee Memberof the Global Non-GMO Foundation. Subclinical hypothyroidism: When to treat | Cleveland Clinic Journal of Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be.". Hypothyroidism - StatPearls - NCBI Bookshelf Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. I posted it to see what anyone had to add. [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. Is so taking anti oxidants might be an idea. Overtreatment, of course, is the hallmark danger of overdiagnosis. Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. Dr Childs guesses that patients on levothyroxine monotherapy may be more prone to cancer because they might be under-treated. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. [9] Otto T, Fandrey J: Thyroid hormone induces hypoxia-inducible factor 1 gene expression through thyroid hormone receptor /retinoid x receptor -dependent activation of hepatic leukemia factor. The Goji Berry: The Jolly Super Food That Gives Yo How to Prevent and Treat Insect Bites Without Hars Supreme Court Rules Drug Companies Exempt From Law Spain Study Confirms Hemp Oil Cures Cancer without Wheatgrass Turns Gray Hair Back to Its Natural Color, Medicinal Cannabis Used To Prevent Cancer Growth. Here members can share stories, find important information and learn from the experiences of others like themselves. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer For a better experience, please enable JavaScript in your browser before proceeding. Whether it should be treated remains controversial. Hypothyroidism results from low levels of thyroid hormone with varied etiology and manifestations. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. I have always found this condition a riddle. They found no significant correlation between T4 sales and breast, colorectal and gastriccancers, but did find a significant correlation for lung cancer (p < 0.05) corrected forsmoking and age. I'm not saying that there Is no link between Synthroid and lung cancer.